Early identification, protocol-based individualized management and follow-up led to a favourable outcome for both the mother and the neonate. This article entails the events of a maternal anaphylactic shock precipitated by intravenous penicillin, foetal distress warranting emergency delivery and acute respiratory distress syndrome (ARDS) following anaphylaxis compounding maternal health. Some advocate pre-pregnancy identification of high-risk patients and confirming sensitivity to allergens 4 albeit their practicality is questionable in low resource countries. 3, 4 The use of antibiotics is implicated in the majority of these critical incidents 5 while neuromuscular blocking agents 5, 6 and latex 7 are also implicated. The effect on neonates is found to be much worse with an increased incidence of intensive care admissions and hypoxaemic encephalopathy. 3 The inherent maternal physiological changes and the foetus hindering venous return especially towards the latter part of the pregnancy contribute to poorer outcomes following anaphylaxis. 1, 2 The incidence is quoted around 1.6 in 100,000 mothers in a UK-based study 1 and 3.8 per 100,000 in the United States. Pertinent identification and management which included a multidisciplinary team culminated in favourable outcomes.Īnaphylaxis during pregnancy is rare. This is a rare case report of a primi mother who developed anaphylactic shock following intravenous penicillin in the background of negative allergic history, resultant foetal distress requiring emergency lower segment caesarian section and delayed onset acute respiratory distress syndrome which was later attributed to anaphylaxis. The management of maternal anaphylaxis does not differ from routine recommendations even though close monitoring and preparedness for early delivery should be embedded in the protocols. Acute respiratory distress syndrome following anaphylaxis is even rarer among the normal population. Consequences of anaphylaxis such as placental insufficiency and subsequent foetal neurocognitive deficits are devastating outcomes. Antibiotics and anaesthetic agents still contribute to majority of the episodes. Maternal anaphylaxis is rare albeit life-threatening critical incident dreaded by many due to negative effects on not only the mother but the foetus as well. All subjects Allied Health Cardiology & Cardiovascular Medicine Dentistry Emergency Medicine & Critical Care Endocrinology & Metabolism Environmental Science General Medicine Geriatrics Infectious Diseases Medico-legal Neurology Nursing Nutrition Obstetrics & Gynecology Oncology Orthopaedics & Sports Medicine Otolaryngology Palliative Medicine & Chronic Care Pediatrics Pharmacology & Toxicology Psychiatry & Psychology Public Health Pulmonary & Respiratory Medicine Radiology Research Methods & Evaluation Rheumatology Surgery Tropical Medicine Veterinary Medicine Cell Biology Clinical Biochemistry Environmental Science Life Sciences Neuroscience Pharmacology & Toxicology Biomedical Engineering Engineering & Computing Environmental Engineering Materials Science Anthropology & Archaeology Communication & Media Studies Criminology & Criminal Justice Cultural Studies Economics & Development Education Environmental Studies Ethnic Studies Family Studies Gender Studies Geography Gerontology & Aging Group Studies History Information Science Interpersonal Violence Language & Linguistics Law Management & Organization Studies Marketing & Hospitality Music Peace Studies & Conflict Resolution Philosophy Politics & International Relations Psychoanalysis Psychology & Counseling Public Administration Regional Studies Religion Research Methods & Evaluation Science & Society Studies Social Work & Social Policy Sociology Special Education Urban Studies & Planning BROWSE JOURNALS
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